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July 10, 2023 3 min read

Can CBD Help with Heroin Addiction?


Heroin addiction is a severe and complex issue that affects countless individuals worldwide. While traditional treatment approaches for heroin addiction include medication-assisted therapy and behavioral interventions, emerging research suggests that cannabidiol (CBD), a non-psychoactive compound derived from the cannabis plant, may hold potential as an adjunctive treatment for heroin addiction.

In this article, we will explore specific examples of how CBD may help individuals struggling with heroin addiction.

  • Alleviating Withdrawal Symptoms: Heroin withdrawal symptoms can be challenging to manage and often contribute to relapse. CBD has shown promise in alleviating the discomfort associated with withdrawal. For instance, a study published in the Journal of Clinical Psychopharmacology demonstrated that CBD significantly reduced anxiety and cravings in individuals with opioid use disorder. This suggests that CBD may assist in managing the psychological and physical symptoms of heroin withdrawal, providing support during the recovery process.
  • Supporting Relapse Prevention: Preventing relapse is a critical aspect of heroin addiction treatment. CBD may play a role in reducing the risk of relapse by influencing brain circuits related to drug reward and craving. Animal studies have indicated that CBD can decrease drug-seeking behaviors and inhibit the reconsolidation of drug-related memories, potentially reducing the likelihood of relapse. Additionally, a study published in Substance Abuse: Research and Treatment reported that individuals using CBD experienced a reduced desire for opioids and exhibited decreased anxiety levels compared to the control group. These findings suggest that CBD may help prevent relapse and promote long-term recovery.
  • Neuroprotective Effects: Heroin use can lead to neurochemical imbalances and damage to brain structures involved in reward and decision-making. CBD has been studied for its neuroprotective properties and its potential to mitigate the harmful effects of substance abuse on the brain. Animal research has shown that CBD can reduce oxidative stress, inflammation, and neuronal damage caused by drug addiction. In a study published in Frontiers in Pharmacology, CBD administration restored the normal functioning of the prefrontal cortex, a brain region crucial for decision-making, in rats with a history of heroin self-administration. These neuroprotective effects of CBD suggest that it may assist in repairing the damage caused by heroin addiction and support cognitive recovery.
  • Craving Reduction: Cravings for heroin can be overwhelming and contribute to relapse. CBD has been investigated for its potential to modulate the brain's reward system and reduce drug cravings. In a double-blind, placebo-controlled study published in Addiction, CBD was found to decrease cue-induced cravings in individuals with heroin use disorder. Another study published in Neuropsychopharmacology reported that CBD reduced cue-induced heroin-seeking behavior in rats, further supporting its potential in suppressing drug cravings. By reducing the intensity of cravings, CBD could help individuals resist the temptation to use heroin and maintain abstinence.
  • Mental Health Support: Heroin addiction often co-occurs with mental health disorders, such as anxiety and depression. CBD has been studied for its anxiolytic and antidepressant properties, which could provide valuable support for individuals with dual diagnoses. Research published in the Journal of Psychopharmacology suggested that CBD exhibited rapid and sustained antidepressant-like effects in animal models, indicating its potential therapeutic value in treating depression. Furthermore, a study published in the Journal of Clinical Psychiatry reported that CBD reduced anxiety levels in individuals with social anxiety disorder. By addressing the comorbid mental health symptoms, CBD may contribute to overall well-being and improve treatment outcomes for individuals with heroin addiction.


While further research is needed to fully understand the role of CBD in treating heroin addiction, the available evidence suggests its potential as a supportive adjunctive treatment. CBD may alleviate withdrawal symptoms, support relapse prevention, exert neuroprotective effects, reduce cravings, and provide mental health support. However, it is important to note that CBD should be used under medical supervision, and individual responses may vary. It is recommended to consult with healthcare professionals familiar with CBD and addiction